MSM Oral Supplement Has Skin Benefits | WholeFoods Magazine As opposed to the outside-in approach of anti-aging creams or serums, this ingredient “influences skin on a genetic level…regulating a select number of genes responsible for inflammation, skin barrier and moisturization,” according the news release. In the randomized, double-blind study, 20 female participants received either 3 g of OptiMSM (in three 1,000-mg capsules) or a placebo (three capsules of rice flour, matched for appearance), daily over 16 weeks. For participants taking OptiMSM, evaluations (taken from expert analysis) at weeks eight and 16 showed statistically significant improvements from the start of the study in reduced crow’s feet lines/wrinkles and improved skin firmness, tone and texture.
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